NUR 641E Week 2 Assignment; Staff Education Presentation - GERD (Gastroesophageal Reflux Disease) and Famotidine

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Natalia Dyer

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Grand Canyon

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NUR 641E Advanced Pathophysiology and Pharmacology for Nurse Educators

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Grand Canyon

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10

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Click to edSittMaaffsteErdtiutlecsattyileon Staff Education 1 Presentation: GERD (Gastroesophageal Reflux Disease) and Famotidine Student Name C o l l e g e o f N u r s i n g & H e a l t h c a r e P r o f e s s i o n s : G r a n d C a n y o n U n i v e r s i t y N U R 6 4 1 : A d v a n c e d P a t h o p h y s i o l o g y a n d P h a r m a c o l o g y f o r N u r s e E d u c a t o r s P r o f e s s o r B e t h a n y H a r d c a s t l e Due Date Click to edit Master title style GERD and Famotidine 2 2 Disease Process GERD • • • Role of stomach acid in GERD Symptoms Complications such as esophagitis or Barrett's esophagus. 3 Drug Class H2 Receptor Antagonists Works by blocking histamine H2 Receptors 4 Pharmacokinetics of Famotidine Absorption: Famotidine is absorbed in the small intestine. Metabolism: Minimal hepatic metabolism. Distribution: Well, distributed in body tissues. Excretion: Primarily excreted unchanged in urine. 5 M e c h a n i s m o f A c t i o n : B l o c k s H 2 r e c e p t o r s o n p a r i e t a l c e l l s , r e d u c i n g a c i d s e c r e t i o n . E ff e c t : D e c r e a s e d g a s t r i c a c i d i t y , p r o v i d i n g r e l i e f f r o m G E R D s y m p t o m s . 6 6 Click to edit Master title style Pharmacodynamics of Famotidine Side Effects, Adverse Reactions, and Safety Issues Common Side Effects: Headache, dizziness, constipation. 7 Adverse Reactions: Rare but may include arrhythmias and hypersensitivity reactions. Safety Issues: Caution in patients with renal impairment. Ethnic, Cultural, and Genetic Considerations Genetic Differences: Variability in drug metabolism, particularly in renal impairment patients. Cultural Considerations: Dietary habits affecting GERD management. Ethnic Considerations: Some populations may have a higher prevalence of GERD, influencing drug efficacy. 8 Monitoring for Desired Effect 9 Effectiveness: Monitor symptom relief (e.g., heartburn, regurgitation). Safety: Regularly assess renal function, especially in elderly or renal-impaired patients. Patient Education: Importance of adherence and lifestyle modifications. References Alshaikh, O. M., Alkhonain, I. M., Anazi, M. S., Alahmari, A. A., Alsulami, F. O., & Alsharqi, A. A. (2021). Assessing the Degree of Gastroesophageal Reflux Disease (GERD) Knowledge Among the Riyadh Population. Cureus, 13(11), e19569. https://doi.org/10.7759/cureus.19569 Banasik, J. L. (2022). Pathophysiology - e-book (7th ed.). Elsevier Health Sciences. McCance, K. L., & Huether, S. E. (2019). Pathophysiology - e-book (8th ed.). Elsevier Health Sciences. Microsoft. (2024). Pills [Stock photo]. Microsoft PowerPoint. Microsoft. (2024). Stomach [Stock photo]. Microsoft PowerPoint. Nguyen K, Dersnah GD, Patel P, et al. Famotidine. [Updated 2024 Jan 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK534778/ Vallerand, A. H., & Sanoski, C. A. (2022). Davis's drug guide for nurses. F. A. Davis Company. Whalen, K. (2022). Lippincott illustrated reviews: Pharmacology (8th ed.). Wolters

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